According to the actual situation of the EPC projects of Long Yan to Long Chuan Railway and Chang Jing Huang Railway with the Practical experience in site supervision. Summarized the characteristics of current EPC mode of railway construction project and Combined the characteristics of the EPC mode of railway engineering project .Put forward the rationalization suggestion on how to carry out the supervision work well and provides a reference for the application research of EPC model and Supervision Enterprises to undertake railway EPC projects.